Left ventricular structure in different types of chronic pressure overload
نویسندگان
چکیده
منابع مشابه
Early improvement in left ventricular diastolic function after relief of chronic right ventricular pressure overload.
Chronic right ventricular pressure overload is associated with left ventricular diastolic dysfunction. Whether or not an abrupt reduction in pulmonary artery pressure in patients with chronic pulmonary hypertension results in early improvement of left ventricular diastolic function is unknown. To assess this, the Doppler indexes of left ventricular diastolic function and echocardiographic measu...
متن کاملComparison of hearts with 2 types of pressure-overload left ventricular hypertrophy.
Comparisons of myocardium remodeled by the 2 most common causes of left ventricular hypertrophy (LVH), hypertension and aortic constriction, are limited. We hypothesized that important differences may exist in the myocardium of hearts with these 2 origins of "pressure overload" LVH. Accordingly, we studied isolated hearts from 3 groups of Dahl salt-sensitive rats, controls, and hearts with matc...
متن کاملRegression of pressure overload-induced left ventricular hypertrophy in mice.
As a prelude to investigating the mechanism of regression of pressure overload-induced left ventricular (LV) hypertrophy (LVH), we studied the time course for the development and subsequent regression of LVH as well as accompanying alterations in cardiac function, histology, and gene expression. Mice were subjected to aortic banding for 4 or 8 wk to establish LVH, and regression was initiated b...
متن کاملSurvival benefits of different antiadrenergic interventions in pressure overload left ventricular hypertrophy/failure.
We observed previously that in rats with aortic banding (Bd), development of left ventricular (LV) hypertrophy is opposed by beta-blockade, whereas interventions interfering with alpha-adrenoceptor function also inhibit interstitial fibrosis. To assess whether these differential structural effects do translate into different effects on LV function and on heart failure mortality, Bd or sham Bd 8...
متن کاملAssessment of left ventricular structure and function in rats subjected to pressure-overload hypertrophy in time.
BACKGROUND Left ventricular hypertrophy (LVH) is an adaptive response to increased haemodynamic load and an independent risk factor for the development of heart failure. Although the pathophysiological features during the development of cardiac hypertrophy have been extensively studied, the time course of LVH is less clearly defined. AIM To define the time-dependency of the LVH process in viv...
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ژورنال
عنوان ژورنال: European Heart Journal Supplements
سال: 2008
ISSN: 1554-2815,1520-1554
DOI: 10.1093/eurheartj/sun015